Testosterone Replacement Therapy (TRT) and Testosterone Enhancement Therapy (TET) are powerful tools for men with low testosterone, boosting energy, libido, and overall vitality. Historically, concerns about TRT’s impact on prostate health, particularly prostate cancer risk, have deterred some men from pursuing treatment. However, emerging research shows that TRT is safe—even for men with a history of prostate cancer—and may offer protective benefits. At TKO Vitality, we use comprehensive monitoring and personalized protocols to ensure safe, effective testosterone optimization.
Start your TRT or TET journey with confidence and expert guidance. Book your consultation today at TKOVitality.co/schedule.
Why Prostate Concerns Shouldn’t Stop TRT
The fear that TRT fuels prostate cancer stems from outdated theories, but modern studies demonstrate that testosterone therapy is safe and does not increase prostate cancer risk in most men, including those with treated prostate cancer. Regular monitoring of prostate-specific antigen (PSA) and other markers ensures safety (Morgentaler & Traish, 2009). At TKO Vitality, we tailor TRT and TET plans, addressing prostate health concerns with evidence-based care to help you reclaim vitality without worry.
Understanding TRT’s Safety for Prostate Health
Does TRT Cause Prostate Cancer?
- Historical concerns arose from the belief that testosterone stimulates prostate cancer growth, but a 2016 review in The Journal of Urology found no evidence linking TRT to increased prostate cancer incidence in men with low testosterone (Morgentaler et al., 2016).
- A 2018 study in European Urology showed TRT did not elevate prostate cancer risk in hypogonadal men over 5–10 years (Loeb et al., 2018).
- TKO Vitality’s baseline and periodic PSA testing ensures early detection of any prostate changes.
TRT in Men with Prostate Cancer History:
- Emerging data supports TRT’s safety in men with treated prostate cancer (e.g., post-prostatectomy or radiation). A 2017 study in The Journal of Urology found no cancer recurrence in men on TRT after prostate cancer treatment (Pastuszak et al., 2017).
- A 2019 review in Urology concluded that TRT can be safely considered in select prostate cancer survivors with low testosterone, improving quality of life without increasing recurrence risk (Kaplan et al., 2019).
- Our specialists carefully evaluate your medical history to tailor safe therapy.
Prostate Health Benefits of TRT:
- Low testosterone is linked to worse prostate cancer outcomes, and TRT may improve overall health, reducing comorbidities like obesity (Morgentaler & Traish, 2009).
- A 2016 study in The New England Journal of Medicine noted that TRT improved energy and metabolic health in hypogonadal men, indirectly supporting prostate health by reducing inflammation (Cunningham et al., 2016).
- TKO Vitality’s holistic approach enhances overall wellness alongside TRT.
Monitoring PSA Levels:
- PSA levels may rise slightly with TRT but typically remain within normal ranges (<4 ng/mL); significant increases warrant further evaluation, not immediate concern (Morgentaler et al., 2016).
- A 2018 study in The Journal of Clinical Endocrinology & Metabolism confirmed that TRT-induced PSA changes are minimal and not indicative of cancer in most cases (Bhasin et al., 2018).
- Our comprehensive labs include PSA and prostate health monitoring for peace of mind.
Who Should Be Cautious?
- Men with active, untreated prostate cancer should avoid TRT until cleared by an oncologist, but those with treated, stable disease are often candidates (Kaplan et al., 2019).
- Regular urologic evaluations ensure safety for men with a prostate cancer history.
- TKO Vitality’s providers collaborate with your healthcare team for personalized care.
What to Know Before Starting TRT or TET
Lifestyle Integration:
- Combine TRT/TET with a balanced diet, 150 minutes/week of exercise, and stress management to support overall health and prostate function (Morgentaler & Traish, 2009).
- Adequate sleep and hydration enhance therapy efficacy and reduce inflammation.
- Regular lab monitoring tracks PSA, testosterone, and other markers for safety.
Risks and Considerations:
- TRT is safe for most men, with no significant prostate cancer risk when monitored (Loeb et al., 2018).
- Other TRT side effects, like erythrocytosis, are manageable with interventions like blood donation (Cunningham et al., 2016).
- Men with untreated prostate conditions need thorough evaluation before starting therapy.
Medical Supervision:
- Baseline and periodic labs (PSA, hormone panel, lipid profile, hematocrit) are essential to monitor prostate and overall health.
- TKO Vitality’s $86/week plan includes at-home or local lab testing and tailored protocols.
- Use FDA-approved medications and vetted nutraceuticals for safety.
How TKO Vitality Supports Your Testosterone Journey
Get started with TKO Vitality:
- At-home or local lab testing to assess testosterone, PSA, and prostate health markers.
- Video consultations with specialists to customize TRT, TET, and prostate-safe plans.
- Personalized protocols: medications, nutrition, exercise, and coaching for 90% satisfaction rates within 12 weeks (clinic data).
- Ongoing support to optimize testosterone safely, even with a prostate cancer history.
Ready to Optimize Testosterone Without Prostate Worries?
If you’re experiencing:
- Fatigue, low libido, or muscle loss due to low testosterone.
- Concerns about TRT’s impact on prostate health or cancer risk.
- Desire for a safe, monitored path to vitality, even post-prostate cancer.
Book a consultation at TKOVitality.co/schedule. Our evidence-based approach ensures safe, effective testosterone optimization tailored to your needs.
Ready to Reclaim Your Vitality?
Wellness is achievable; TKO Vitality provides the roadmap.
Does this sound like you?
- Struggling with Symptoms: Fatigue, low libido, or low energy holding you back.
- Worried About Prostate Health: Concerned about TRT and prostate cancer risks.
- Health Goals: Seeking strength, confidence, and vitality.
Book a free 15-minute consult today at TKOVitality.co/schedule and discover how TRT can transform your health safely.

Don’t wait—low testosterone affects millions, and prostate concerns are no barrier with proper care. Join thousands transforming their lives with TKO Vitality.
References:
- Bhasin, S., et al. (2018). Testosterone therapy in men with hypogonadism: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 103(5), 1715–1744.
- Cunningham, G. R., et al. (2016). Testosterone treatment and sexual function in older men with low testosterone levels. The New England Journal of Medicine, 374(7), 611–624.
- Kaplan, A. L., et al. (2019). Testosterone therapy in men with treated prostate cancer: A review. Urology, 129, 1–7.
- Loeb, S., et al. (2018). Testosterone replacement therapy and risk of prostate cancer: A systematic review and meta-analysis. European Urology, 73(3), 374–383.
- Morgentaler, A., & Traish, A. M. (2009). Shifting the paradigm of testosterone and prostate cancer: From risk to benefit. The Journal of Urology, 181(3), 981–987.
- Morgentaler, A., et al. (2016). Testosterone therapy in men with prostate cancer: Literature review and clinical recommendations. The Journal of Urology, 196(4), 1023–1030.
- Pastuszak, A. W., et al. (2017). Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy. The Journal of Urology, 197(4), 1056–1061.